TLR8 agonist 6

• UNSPSC Description:

  TLR8 agonist 6 (Compound A) is a TLR8 agonist, with an EC50 of 0.052 μM. TLR8 agonist 6 induces IL-12p40 production in human PBMC (EC50: 0.031 μM). TLR8 agonist 6 can be used in the research of virus resistance, infection resistance, autoimmunity, tumor, etc[1].

• Target Antigen:

  Toll-like Receptor (TLR)

• Type:

  Reference compound

• Related Pathways:

  Immunology/Inflammation

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/tlr8-agonist-6.html

• Solubility:

  10 mM in DMSO

• Smiles:

  CN(C)C(C(C=N1)=CC2=C1C(N[C@](CNC(C)=O)(C)CCCC)=NC(N)=N2)=O

• Molecular Weight:

  387.48

• References & Citations:

  [1]Liang Bo, et al. 2-aminopyrimidine compounds and pharmaceutical composition and application thereof. Patent. CN112390795.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  2616605-55-9