TLR8 agonist 2

• Description :

  TLR8 agonist 2 is a potent and selective TLR8 agonist with an EC50 of 3 nM for human TLR8. TLR8 agonist 2 shows less active against human TLR7 (EC50 of 33.33 μM) [1].

• UNSPSC :

  12352005

• Target :

  Toll-like Receptor (TLR)

• Type :

  Reference compound

• Related Pathways :

  Immunology/Inflammation

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Inflammation/Immunology

• Assay Protocol :

  https://www.medchemexpress.com/tlr8-agonist-2.html

• Solubility :

  10 mM in DMSO

• Smiles :

  CCCC[C@@](CC1=NN=CN1)(C)NC2=NC(N)=NC3=C2C=CN=C3

• Molecular Formula :

  C16H22N8

• Molecular Weight :

  326.40

• References & Citations :

  [1]Zhe Cai, et al. Tlr8 agonist. WO2020057604A1.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• Isoform :

  TLR7; TLR8

• CAS Number :

  [2412937-64-3]