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TLR8 agonist 8

CAT: 0013-GTR19233962-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19233962-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
TLR8 agonist8 (Compound II-72) is a stable small molecule TLR8 agonist with an EC50 of 0.25-1 μM, inducing TNFα secretion. It demonstrated potent in vivo antitumor efficacy in a MC38-HER2 mouse model, achieving 89% tumor growth inhibition, supporting its use in immuno-oncology research.
CAS Number
3034750-58-5
Field of Research
Immunology & Inflammation, Immunology & Inflammation; Pharmacology & Drug Discovery
Smiles
C (NC=1C=C2C (=NC1) CCN (C (CNC ([C@H] (CC3=CC=CC=C3) NC (CNC (CNC (CCCCCN4C (=O) C=CC4=O) =O) =O) =O) =O) =O) C2) (=O) C5 (CC5) C=6C=C7C (=CC6) C=C (C (N (CCC) CCO) =O) CC (N) =N7
Molecular Formula
C53H63N11O10
Molecular Weight
1014.14
Storage Conditions
-20°C
Notes
For research use only.

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