TLR8 agonist 2 (hydrochloride)

• UNSPSC Description:

  TLR8 agonist 2 hydrochloride is a potent and selective TLR8 agonist with an EC50 of 3 nM for human TLR8. TLR8 agonist 2 hydrochloride shows less active against human TLR7 (EC50 of 33.33 μM)[1].

• Target Antigen:

  Toll-like Receptor (TLR)

• Type:

  Reference compound

• Related Pathways:

  Immunology/Inflammation

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/tlr8-agonist-2-hydrochloride.html

• Solubility:

  10 mM in DMSO

• Smiles:

  CCCC[C@@](CC1=NN=CN1)(C)NC2=NC(N)=NC3=C2C=CN=C3.[x].Cl

• References & Citations:

  [1]Zhe Cai, et al. Tlr8 agonist. WO2020057604A1.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  2412937-65-4