ATR-IN-29

ATR-IN-29

• CAS Number: 2761193-67-1
• UNSPSC Description: ATR-IN-29 is a potent and orally active ATR kinase inhibitor with an IC50 value of 1 nM. ATR-IN-29 shows antiproliferative activity[1].
• Target Antigen: ATM/ATR
• Type: Reference compound
• Related Pathways: Cell Cycle/DNA Damage;PI3K/Akt/mTOR
• Applications: Cancer-Kinase/protease
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/atr-in-29.html
• Solubility: 10 mM in DMSO
• Smiles: CC1=C2N(N=C(N3[C@@H](COCC3)C)C=C2C4=CC=NN4C)C(C5=NNC=C5)=N1
• Molecular Weight: 378.43
• References & Citations: [1]Sui Xiong Cai, et al. Substituted imidazo[1,5-b]pyridazine compounds as kinase inhibitors and use thereof. WO2022135560A1.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported