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ATR-IN-29

CAT: 0804-HY-153729Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-153729Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
ATR-IN-29 is a potent and orally active ATR kinase inhibitor with an IC50 value of 1 nM. ATR-IN-29 shows antiproliferative activity[1].
CAS Number
2761193-67-1
UNSPSC
12352005
Target
ATM/ATR
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; PI3K/Akt/mTOR
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/atr-in-29.html
Solubility
10 mM in DMSO
Smiles
CC1=C2N(N=C(N3[C@@H](COCC3)C)C=C2C4=CC=NN4C)C(C5=NNC=C5)=N1
Molecular Formula
C19H22N8O
Molecular Weight
378.43
References & Citations
[1]Sui Xiong Cai, et al. Substituted imidazo[1,5-b]pyridazine compounds as kinase inhibitors and use thereof. WO2022135560A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
ATR

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