ATR-IN-16

ATR-IN-16

• CAS Number: 2756589-62-3
• UNSPSC Description: ATR-IN-16 (compound 46) is a potent ATR kinase inhibitor. ATR-IN-16 shows good anticancer activity in LoVo cells, with an IC50 of 410 nM[1].
• Target Antigen: ATM/ATR
• Type: Reference compound
• Related Pathways: Cell Cycle/DNA Damage;PI3K/Akt/mTOR
• Applications: Cancer-Kinase/protease
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/atr-in-16.html
• Solubility: 10 mM in DMSO
• Smiles: CC1=NNC(NC2=CC(C3=C(C=NN3C)C)=CC(N4CCOC[C@H]4C)=N2)=C1
• Molecular Weight: 367.45
• References & Citations: [1]Bo Shan, et al. Atr inhibitors and uses thereof. WO2022002245A1.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported