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CDK4/6-IN-17

CAT: 0804-HY-153704Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-153704Size:1 Each
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Description
CDK4/6-IN-17 (Compound 12) is a CDK4/6 inhibitor (IC50: 50: 10-100 nM) . CDK4/6-IN-17 inhibits tumor growth in COLO205 xenograft tumors[1].
CAS Number
2035069-96-4
UNSPSC
12352005
Target
CDK
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/cdk4-6-in-17.html
Solubility
10 mM in DMSO
Smiles
FC([C@H]1N2C3=CC(C4=NC(NC5=CC=C(C=N5)CN6CCN(CC6)CC)=NC=C4F)=CC(F)=C3N=C2CC1)F
Molecular Formula
C27H28F4N8
Molecular Weight
540.56
References & Citations
[1]Zhao X, et al. Preparation of benzopyrroloimidazolyl compounds as CDK4/6 kinase inhibitors. World Intellectual Property Organization, WO2016173505 A1. 2016-11-03.|[2]Zhao Xingdong. A kind of kinase inhibitor. Patent. CN107849012.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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