CDK4/6-IN-7

CDK4/6-IN-7

• CAS Number: 2649120-20-5
• UNSPSC Description: CDK4/6-IN-7 is a potent, selective and orally active CDK4/6 inhibitor, with IC50s of 1.58 and 4.09 nM, respectively. CDK4/6-IN-7 can be used for the research of breast cancer[1].
• Target Antigen: CDK
• Type: Reference compound
• Related Pathways: Cell Cycle/DNA Damage
• Applications: Cancer-Kinase/protease
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/cdk4-6-in-7.html
• Solubility: 10 mM in DMSO
• Smiles: O=C(C1=CC=CC=C1Cl)NNC(N2CCC[C@@H]2C(NC3=CC=CN=C3)=O)=O
• Molecular Weight: 387.82
• References & Citations: [1]Liang JW, et, al. Synthesis and identification of a novel skeleton of N-(pyridin-3-yl) proline as a selective CDK4/6 inhibitor with anti-breast cancer activities. Bioorg Chem. 2022 Feb;119:105547.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported