Products for Research Use Only

CDK4/6-IN-23

CAT: 0931-T204550-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T204550-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
CDK
Related Pathways
Cell Cycle/Checkpoint
Bioactivity
CDK4/6-IN-23 (Compound 42) is a potent and selective inhibitor of CDK4/6, displaying an IC50 of 11 nM for CDK6. This compound significantly activates immune cells and enhances IL-3 production. In mice undergoing 5-FU chemotherapy, CDK4/6-IN-23 demonstrates dual bone marrow protection and immunomodulatory effects.
Smiles
CC(=O)N1CCC2(CC1)CC(=O)C3=C(O2)C=C(C=C3)C4=NC(=NC=C4F)NC5=NC=C(C=C5)N6CCN(CC6)C(=O)C7CC7
Molecular Formula
C32H34FN7O4
Molecular Weight
599.655
Shipping Conditions
Ice Packs
Storage Temperature
-20°C