CDK4/6-IN-9
CAT:
804-HY-115992
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
CDK4/6-IN-9
- CAS Number: 2688098-02-2
- UNSPSC Description: CDK4/6-IN-9 (compound 10) is a selective CDK4/6 inhibitor with an IC50 of 905 nM for CDK6/cyclin D1. CDK4/6-IN-9 has the potential for multiple myeloma (MM) research[1].
- Target Antigen: CDK
- Type: Reference compound
- Related Pathways: Cell Cycle/DNA Damage
- Applications: Cancer-Kinase/protease
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/cdk4-6-in-9.html
- Solubility: 10 mM in DMSO
- Smiles: CN1C=C(C2=NC(NC3=NC=C(CN4CCNCC4)C=C3)=NC=C2F)C5=CC=CN=C51
- Molecular Weight: 418.47
- References & Citations: [1]Kai Yuan, et al. Discovery of novel and orally bioavailable CDK 4/6 inhibitors with high kinome selectivity, low toxicity and long-acting stability for the treatment of multiple myeloma. Eur J Med Chem. 2022 Jan 15;228:114024.
- Shipping Conditions: Room temperature
- Clinical Information: No Development Reported