CDK4/6-IN-16

CDK4/6-IN-16

• CAS Number: 1169694-98-7
• UNSPSC Description: CDK4/6-IN-16 (example 195) is a potent CDK4 and CDK6 inhibitor, with an IC50 of 0.013 μM for CDK4. CDK4/6-IN-16 can be used for the research of CDK4-mediated disorders, such as cancer[1].
• Target Antigen: CDK
• Type: Reference compound
• Related Pathways: Cell Cycle/DNA Damage
• Applications: Cancer-Kinase/protease
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/cdk4-6-in-16.html
• Solubility: 10 mM in DMSO
• Smiles: FC1=NC=CC2=C1N(C3CCCC3)C4=C2C=NC(NC5=NC=C(N6CCC(CC6)N(CCO)C)C=C5)=N4
• Molecular Weight: 504.60
• References & Citations: [1]Richard V. Connors, et al. Fused pyridine, pyrimidine and triazine compounds as cell cycle inhibitors. WO2009085185A1.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported