HER2-IN-14
CAT:
804-HY-153557A
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
HER2-IN-14
- CAS Number: 2414056-35-0
- UNSPSC Description: HER2-IN-14 (Compound 34) is an HER2 inhibitor with an IC50 of 18 nM. HER2-IN-14 also inhibits wt-EGFR with an IC50 of 6.3 μM[1].
- Target Antigen: EGFR
- Type: Reference compound
- Related Pathways: JAK/STAT Signaling;Protein Tyrosine Kinase/RTK
- Applications: Cancer-Kinase/protease
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/her2-in-14.html
- Solubility: 10 mM in DMSO
- Smiles: ClC(C=C1NC2=NC=NC3=C2C(O[C@@H]4C(F)(CN(CC4)C)F)=C(OC)C=C3)=C(C=C1)OC5=CC6=NC=NN6C=N5
- Molecular Weight: 568.96
- References & Citations: [1]Ding Zhou, et al. Quinazoline derivatives as antitumor agents. Patent WO2020057511A1.
- Shipping Conditions: Room temperature
- Clinical Information: No Development Reported