BJE6-106

CAT: 0931-T10555Size: 1 mgDry Ice: NoHazardous: No
CAT#:0931-T10555Size:1 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1564249-38-2
Target
PKC|||Caspase|||Apoptosis|||JNK
Related Pathways
Chromatin/Epigenetic|||Proteases/Proteasome|||Apoptosis|||Cytoskeletal Signaling|||MAPK
Bioactivity
BJE6-106 (B106) is a selective PKC? inhibitor (IC50 = 0.05 ?M) with 1000-fold higher selectivity for PKC? than PKC? (IC50 = 50 ?M) . BJE6-106 induces caspase-dependent apoptosis, activates the JNK pathway and H2AX, and can be used to study NRAS-mutated melanoma.
Smiles
O=CC1=CC(=CC=2C=CC(OC12)(C)C)CCN3C=4C=CC=CC4C=5C=CC=CC53
Molecular Formula
C26H23NO2
Molecular Weight
381.47
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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