HER2-IN-8

• Description:

  HER2-IN-8 is a HER-2 inhibitor extracted from patent WO2021179274A1 compound 107. HER2-IN-8 can be used for the research of cancer and inflammation[1].

• UNSPSC:

  12352005

• Target:

  EGFR

• Type:

  Reference compound

• Related Pathways:

  JAK/STAT Signaling; Protein Tyrosine Kinase/RTK

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Cancer; Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/her2-in-8.html

• Solubility:

  10 mM in DMSO

• Smiles:

  COC1=C (C2=C (N=CN=C2NC3=CC (C) =C (C=C3) OC4=CN5N=CN=C5N=C4) C=N1) O[C@@H]6CCN (CC6 (F) F) C

• Molecular Formula:

  C26H25F2N9O3

• Molecular Weight:

  549.53

• References & Citations:

  [1]Zhou D, et, al. ErbB RECEPTOR INHIBITORS AS ANTI-TUMOR AGENTS. WO2021179274A1.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• Isoform:

  ErbB2/HER2

• CAS Number:

  2704630-49-7