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HER2-IN-18

CAT: 0804-HY-163419Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-163419Size:1 Each
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Description
HER2-IN-18 is a HER2 inhibitor, with an IC50 less than 200 nM for HER-YVMA and HER-WT. HER2-IN-18 can be used for cancer research[1].
UNSPSC
12352005
Target
EGFR
Type
Reference compound
Related Pathways
JAK/STAT Signaling; Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/her2-in-18.html
Solubility
10 mM in DMSO
Smiles
C=CC(N1CCC(C1)C2=C3C(NC4=CC(C)=C(C=C4)OC5=CC6=NC=NN6C=C5)=NC=NN3C=C2)=O
Molecular Formula
C26H24N8O2
Molecular Weight
480.52
References & Citations
[1]Svitlana KULYK, et al. Compounds and methods for modulating her2. Patent. WO2024044570
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
EGFR/ErbB1/HER1; ErbB2/HER2

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