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HER2-IN-14

CAT: 0931-T75165-01Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0931-T75165-01Size:100 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2414056-35-0
Target
EGFR, Others
Related Pathways
Angiogenesis, Others, JAK/STAT signaling, Tyrosine Kinase/Adaptors
Bioactivity
HER2-IN-14 (Compound 34) is a potent HER2 inhibitor with an IC50 of 18 nM and demonstrates inhibitory activity against wild-type EGFR (wt-EGFR) with an IC50 of 6.3 μM [1].
Smiles
O(C=1C=2C(NC3=CC(Cl)=C(OC4=CC=5N(C=N4)N=CN5)C=C3)=NC=NC2C=CC1OC)[C@@H]6C(F)(F)CN(C)CC6
Molecular Formula
C26H23ClF2N8O3
Molecular Weight
568.96
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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