PROTAC BTK Degrader-3

PROTAC BTK Degrader-3

• CAS Number: 2563861-90-3
• UNSPSC Description: PROTAC BTK Degrader-3 is a potent BTK degrader with a DC50 value of 10.9 nM of BTK degradation in Mino cells. PROTAC BTK Degrader-3 has the potential for B-cell malignancies, including chronic lymphoid malignancies research[1].
• Target Antigen: Btk; PROTACs
• Type: Reference compound
• Related Pathways: PROTAC;Protein Tyrosine Kinase/RTK
• Applications: Cancer-Kinase/protease
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/protac-btk-degrader-3.html
• Solubility: 10 mM in DMSO
• Smiles: O=C1C2=CC=C(N3CC(C3)N4CC(C4)N5CCC(CC5)N6N=C(C7=C6N=CN=C7N)C8=CC=C(OC9=CC=CC=C9)C=C8)C=C2C(N1C%10C(NC(CC%10)=O)=O)=O
• Molecular Weight: 752.82
• References & Citations: [1]Zhangchen, et al. Salt of compound for degrading btk, crystal form thereof, and use thereof in medicine. Patent WO2022052950A1.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported