PROTAC BTK Degrader-2

PROTAC BTK Degrader-2

• CAS Number: 2250382-66-0
• UNSPSC Description: PROTAC BTK Degrader-2 is a potent BTK PROTAC degrader. PROTAC BTK Degrader-2 effectively reduces BTK protein levels[1].
• Target Antigen: Btk; PROTACs
• Type: Reference compound
• Related Pathways: PROTAC;Protein Tyrosine Kinase/RTK
• Applications: Cancer-Kinase/protease
• Field of Research: Others
• Assay Protocol: https://www.medchemexpress.com/protac-btk-degrader-2.html
• Solubility: 10 mM in DMSO
• Smiles: O=C(N1C[C@H](N2N=C(C3=CC=C(OC4=CC=C(F)C=C4F)C=C3)C(C(N)=O)=C2N)CCC1)OCCOCCOCCOCCOCCOCCNC5=CC=CC(C(N6C(CC7)C(NC7=O)=O)=O)=C5C6=O
• Molecular Weight: 976.97
• References & Citations: [1]Zorba A, et, al. Delineating the role of cooperativity in the design of potent PROTACs for BTK. Proc Natl Acad Sci U S A. 2018 Jul 31;115(31):E7285-E7292.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported