ATR-IN-10

ATR-IN-10

• CAS Number: 2713577-93-4
• UNSPSC Description: ATR-IN-10 is a potent and highly selective inhibitor of ataxia telangiectasia mutated and Rad3-Related (ATR) kinase with an IC50 value of 2.978 μM.
• Target Antigen: ATM/ATR
• Type: Reference compound
• Related Pathways: Cell Cycle/DNA Damage;PI3K/Akt/mTOR
• Applications: Cancer-Kinase/protease
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/atr-in-10.html
• Solubility: 10 mM in DMSO
• Smiles: C[C@H]1N(C2=C3C=C(C4=CC=CC=C4)C=CC3=NC(C5=CC=CC6=C5C=CN6)=N2)CCOC1
• Molecular Weight: 420.51
• References & Citations: [1]Bin H, et al. Discovery of a potent and highly selective inhibitor of ataxia telangiectasia mutated and Rad3-Related (ATR) kinase: Structural activity relationship and antitumor activity both in vitro and in vivo. Eur J Med Chem. 2022 Feb 12;232:114187.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported