ATR-IN-22

CAT: 0804-HY-153400Size: 1 EachDry Ice: NoHazardous: No

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CAT#:0804-HY-153400Size:1 Each

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Description

ATR-IN-22 (Compound 34) is an orally active ATR inhibitor. ATR-IN-22 inhibits MIAPaCa-2 proliferation (IC50 [1].

CAS Number

2905312-07-2

UNSPSC

12352005

Target

ATM/ATR

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage; PI3K/Akt/mTOR

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/atr-in-22.html

Solubility

10 mM in DMSO

Smiles

N#CC1(CCC(CC1)N(C)C)C2=CC(N3[C@@H](COCC3)C)=NC4=C2C=CN=C4C5=NNC=C5

Molecular Formula

C25H31N7O

Molecular Weight

445.56

References & Citations

[1]Xie, Yuli, et al. Naphthyridine derivative as ATR inhibitor and method for preparing same. Patent. WO2023016529. 2023-02-16.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

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