ATR-IN-15
CAT:
804-HY-147567
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
ATR-IN-15
- CAS Number: 2756665-52-6
- UNSPSC Description: ATR-IN-15 (compound 1) is an orally active and potent ATR kinase inhibitor, with an IC50 of 8 nM. ATR-IN-15 also inhibits human colon tumor cells LoVo, DNA-PK and PI3K, with IC50 values of 47, 663 and 5131 nM, respectively[1].
- Target Antigen: ATM/ATR; DNA-PK; PI3K
- Type: Reference compound
- Related Pathways: Cell Cycle/DNA Damage;PI3K/Akt/mTOR
- Applications: Cancer-Kinase/protease
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/atr-in-15.html
- Solubility: 10 mM in DMSO
- Smiles: CC1=NC(C2=CC=NN2)=C3N=C(C=C(N13)N4[C@H](C)COCC4)C5=CC=NN5C
- Molecular Weight: 378.43
- References & Citations: [1]Xin Li, et al. Imidazopyrimidine derivative, preparation method therefor and medical use thereof. WO2022002243A1.
- Shipping Conditions: Room temperature
- Clinical Information: No Development Reported