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BCR-ABL-IN-7

CAT: 0804-HY-153008Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-153008Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
BCR-ABL-IN-7 (compound 4) is a WT and T315I mutant ABL kinases inhibitor. BCR-ABL-IN-7 effectively inhibits activities of WT and T315I mutant ABL kinases. BCR-ABL-IN-7 can be used for the research of chronic myeloid leukemia (CML) research[1].
CAS Number
688050-42-2
UNSPSC
12352005
Hazard Statement
H302, H315, H319
Target
Bcr-Abl
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/bcr-abl-in-7.html
Purity
99.66
Solubility
DMSO : 2 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C(C1=C(NC(C2=NOC(C3=CC=C(F)C=C3)=C2)=O)SC4=C1CCCC4)N
Molecular Formula
C19H16FN3O3S
Molecular Weight
385.41
Precautions
H302, H315, H319
References & Citations
[1]Cao R, et al. Discovery of 2-Acylaminothiophene-3-Carboxamides as Multitarget Inhibitors for BCR-ABL Kinase and Microtubules. J Chem Inf Model. 2015 Nov 23;55 (11) :2435-42.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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