BCR-ABL-IN-4

CAT: 0804-HY-142922Size: 1 EachDry Ice: NoHazardous: No

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CAT#:0804-HY-142922Size:1 Each

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Description

BCR-ABL-IN-4 is a BCR-ABL inhibitor with anticancer effects. BCR-ABL-IN-4 inhibits the cancer cell growth with IC50 values of 0.67 nM and 16 nM for K562 cells and BCR-ABL T315I transfected Ba/F3 cells, respectively (WO2021143927A1; compound 11) [1].

CAS Number

2669790-59-2

UNSPSC

12352005

Target

Bcr-Abl

Type

Reference compound

Related Pathways

Protein Tyrosine Kinase/RTK

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/bcr-abl-in-4.html

Solubility

10 mM in DMSO

Smiles

ClC(F)(F)OC(C=C1)=CC=C1NC(C2=CC(C3=CN=C(CN(C4CC4)C5=O)C5=C3)=C(N6C[C@@H](CC6)O)N=C2)=O

Molecular Formula

C27H24ClF2N5O4

Molecular Weight

555.96

References & Citations

[1]Yinsheng Zhang, et al. Compound acting as bcr-abl inhibitor. WO2021143927A1.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

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Alternative Products

Catalog	Name
T63932-01	BCR-ABL-IN-4
FP-003	BCR/ABL
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abx376631-01	BCR/ABL P210 Fusion Protein (BCR/ABL) Antibody
BA8807-1	BCR-ABL-IN-8
XKB36918-01	BCR-ABL-IN-2
442184-01	Bcr-abl Inhibitor
MBS5800152	BCR-ABL-IN-3
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BCR-ABL-IN-4

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