BCR-ABL-IN-11

CAT: 0804-HY-169608Size: 1 EachDry Ice: NoHazardous: No

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Description

BCR-ABL-IN-11 (Compound 2) is a BCR-ABL inhibitor. BCR-ABL-IN-11 shows anticancer activity against chronic myelogenous leukemia (CML) (IC50 of 129.61 μM for K562 cells) [1].

CAS Number

2362-25-6

UNSPSC

12352211

Target

Bcr-Abl

Related Pathways

Protein Tyrosine Kinase/RTK

Field of Research

Cancer

Smiles

O=C(C1=CC=C(C=C1)N)NC2=CC=CC(NC(C3=CC=C(C=C3)N)=O)=C2

Molecular Formula

C20H18N4O2

Molecular Weight

346.38

References & Citations

[1]Peng H, et al. Identification of novel inhibitors of BCR-ABL tyrosine kinase via virtual screening. Bioorg Med Chem Lett. 2003 Nov 3;13 (21) :3693-9.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

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BCR-ABL-IN-11

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