BCR-ABL-IN-8
CAT:
804-HY-156148-02
Size:
10 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
BCR-ABL-IN-8
- CAS Number: 1808288-49-4
- UNSPSC Description: BCR-ABL-IN-8 (compound 26f) is a BCR-ABL inhibitor containing trimethoxy group[1].
- Target Antigen: Bcr-Abl
- Type: Reference compound
- Related Pathways: Protein Tyrosine Kinase/RTK
- Applications: Cancer-Kinase/protease
- Field of Research: cancer
- Assay Protocol: https://www.medchemexpress.com/bcr-abl-in-8.html
- Solubility: DMSO : 100 mg/mL (ultrasonic)
- Smiles: O=C(C1=CC(OC)=C(C(OC)=C1)OC)NC2=CC=C(C)C(NC(C3=CN=C(NC4=CC=C(C)C(N)=C4)N=C3NC)=O)=C2
- Molecular Weight: 571.63
- References & Citations: [1]Liang X, et al. Discovery of 2-((3-Amino-4-methylphenyl)amino)-N-(2-methyl-5-(3-(trifluoromethyl)benzamido)phenyl)-4-(methylamino)pyrimidine-5-carboxamide (CHMFL-ABL-053) as a Potent, Selective, and Orally Available BCR-ABL/SRC/p38 Kinase Inhibitor for Chronic Myeloid Leukemia. J Med Chem. 2016 Mar 10;59(5):1984-2004.
- Shipping Conditions: Room Temperature
- Clinical Information: No Development Reported