BCR-ABL-IN-3

BCR-ABL-IN-3

• CAS Number: 2240191-12-0
• UNSPSC Description: BCR-ABL-IN-3 is a potent and irreversible Bcr-Abl inhibitor with an IC50 of ≤100 nM for Ba/F3Bcr-AblT3151. BCR-ABL-IN-3 has anti-cancer activity[1].
• Target Antigen: Bcr-Abl
• Type: Reference compound
• Related Pathways: Protein Tyrosine Kinase/RTK
• Applications: Cancer-Kinase/protease
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/bcr-abl-in-3.html
• Solubility: 10 mM in DMSO
• Smiles: O=C(C1=CC(C2=CSN=C2)=C(N3C[C@H](O)CC3)N=C1)NC4=CC=C(OC(F)(Cl)F)C=C4
• Molecular Weight: 466.89
• References & Citations: [1]Hanyi Wang, et al. (hetero)arylamide compound for inhibiting protein kinase activity. WO2018133826A1.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported