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BCR-ABL-IN-3

CAT: 0804-HY-136526Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-136526Size:1 Each
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Description
BCR-ABL-IN-3 is a potent and irreversible Bcr-Abl inhibitor with an IC50 of ≤100 nM for Ba/F3Bcr-AblT3151. BCR-ABL-IN-3 has anti-cancer activity[1].
CAS Number
2240191-12-0
UNSPSC
12352005
Target
Bcr-Abl
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/bcr-abl-in-3.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=CC(C2=CSN=C2)=C(N3C[C@H](O)CC3)N=C1)NC4=CC=C(OC(F)(Cl)F)C=C4
Molecular Formula
C20H17ClF2N4O3S
Molecular Weight
466.89
References & Citations
[1]Hanyi Wang, et al. (hetero) arylamide compound for inhibiting protein kinase activity. WO2018133826A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Bcr-Abl

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