ARS-2102

• UNSPSC Description:

  ARS-2102 is a potent covalent KRAS G12C inhibitor for use in cancer research[1].

• Target Antigen:

  Ras

• Type:

  Reference compound

• Related Pathways:

  GPCR/G Protein;MAPK/ERK Pathway

• Applications:

  Cancer-Kinase/protease

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/ars-2102.html

• Solubility:

  10 mM in DMSO

• Smiles:

  FC1=C(C2=C(C=CC=C2O)F)C(Cl)=CC3=C1N=C(N4CC(C4)N(C)C)N=C3N5[C@H](CN([C@@H](C5)C)C(C=C)=O)C

• Molecular Weight:

  557.03

• References & Citations:

  [1]Xiaogen Yang, et al. Hindered Biaryl Bond Construction and Subsequent Diastereomeric Crystallization to Produce an Atropisomeric Covalent KRASG12C Inhibitor ARS-2102.Org. Process Res. Dev. 2022.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  2098509-21-6