ARS-2102

• Description :

  ARS-2102 is a potent covalent KRAS G12C inhibitor for use in cancer research[1].

• UNSPSC :

  12352005

• Target :

  Ras

• Type :

  Reference compound

• Related Pathways :

  GPCR/G Protein; MAPK/ERK Pathway

• Applications :

  Cancer-Kinase/protease

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/ars-2102.html

• Solubility :

  10 mM in DMSO

• Smiles :

  FC1=C(C2=C(C=CC=C2O)F)C(Cl)=CC3=C1N=C(N4CC(C4)N(C)C)N=C3N5[C@H](CN([C@@H](C5)C)C(C=C)=O)C

• Molecular Formula :

  C28H31ClF2N6O2

• Molecular Weight :

  557.03

• References & Citations :

  [1]Xiaogen Yang, et al. Hindered Biaryl Bond Construction and Subsequent Diastereomeric Crystallization to Produce an Atropisomeric Covalent KRASG12C Inhibitor ARS-2102.Org. Process Res. Dev. 2022.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [2098509-21-6]