ARS-1323

• Description :

  ARS-1323 (Example 30, No. 227) is the racemate of ARS-1620. ARS-1323 is a novel inhibitor of mutant K-ras G12C[1].

• UNSPSC :

  12352005

• Hazard Statement :

  H302, H315, H319, H335

• Target :

  Ras

• Type :

  Reference compound

• Related Pathways :

  GPCR/G Protein; MAPK/ERK Pathway

• Applications :

  Cancer-Kinase/protease

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/ARS-1323.html

• Purity :

  99.67

• Solubility :

  DMSO : 100 mg/mL (ultrasonic)

• Smiles :

  O=C(C=C)N1CCN(C2=NC=NC3=C2C=C(Cl)C(C4=C(O)C=CC=C4F)=C3F)CC1

• Molecular Formula :

  C21H17ClF2N4O2

• Molecular Weight :

  430.84

• Precautions :

  H302, H315, H319, H335

• References & Citations :

  [1]Liansheng Li, et al. Inhibitors of kras g12c. WO 2015054572 A1.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• Isoform :

  K-Ras

• CAS Number :

  [1698024-73-5]