ARS-1620 intermediate

• Description :

  ARS-1620 intermediate is an intermediate in the synthesis of a K-RasG12C inhibitor ARS1620 (HY-U00418) [1].

• UNSPSC :

  12352005

• Hazard Statement :

  H302-H315-H319-H335

• Target :

  Drug Intermediate

• Related Pathways :

  Others

• Field of Research :

  Others

• Smiles :

  ClC1=C(Br)C(F)=C(N=CN=C2N3CCN(C(OC(C)(C)C)=O)CC3)C2=C1

• Molecular Formula :

  C17H19BrClFN4O2

• Molecular Weight :

  445.71

• Precautions :

  P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

• References & Citations :

  [1]Janes, M. R., et al., (2018) . Targeting KRAS Mutant Cancers with a Covalent G12C-Specific Inhibitor. Cell, 172 (3), 578–589.e17.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound2

• Clinical Information :

  No Development Reported

• CAS Number :

  [1698027-20-1]