MRV03-037

• Description:

  MRV03-037 is a selective colibactin-activated peptidase (ClbP) inhibitor that blocks the genotoxic effect of Colibactin (HY-145930) on eukaryotic cells. MRV03-037 prevents gut bacterial genotoxin production[1].

• UNSPSC:

  12352211

• Target:

  Bacterial

• Type:

  Reference compound

• Related Pathways:

  Anti-infection

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Infection

• Assay Protocol:

  https://www.medchemexpress.com/mrv03-037.html

• Solubility:

  10 mM in DMSO

• Smiles:

  CCCCCC(N[C@H](CC(N)=O)B1OC(C)(C)C(C)(C)O1)=O

• Molecular Formula:

  C15H29BN2O4

• Molecular Weight:

  312.21

• References & Citations:

  [1]Volpe MR, et al. A small molecule inhibitor prevents gut bacterial genotoxin production. Nat Chem Biol. 2022 Oct 17.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [2797066-16-9]