SPP-037

• Target :

  Endogenous Metabolite|||FAK

• Related Pathways :

  Tyrosine Kinase/Adaptors|||Angiogenesis|||Metabolism|||Cytoskeletal Signaling

• Bioactivity :

  SPP-037 is an orally active selective inhibitor of ST6GAL1, with an IC50 of 3.59 ?M. It exhibits anti-migration activity against MDA-MB-231 cells by inhibiting integrin ?2,6-sialylation and the integrin-FAK-paxillin pathway. In MDA-MB-231 xenograft mouse models, SPP-037 demonstrates antitumor properties. This compound is applicable in breast cancer research.

• Molecular Formula :

  C36H50ClN3O9S

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C