PPA-037

• Target :

  CDK

• Related Pathways :

  Cell Cycle/Checkpoint

• Bioactivity :

  PPA-037 is an orally active and highly selective inhibitor of cyclin-dependent kinase 12 (CDK12) . It induces the degradation of Cyclin K, thereby enhancing antiproliferative effects on tumor cells. PPA-037 holds potential for use in cancer research.

• Smiles :

  N(CC1=CC=C(C=C1)C2=CC=CC=N2)C=3N4C(=C(C=N4)C5CC5)N=C(N[C@H]6CCNC6)C3

• Molecular Formula :

  C25H27N7

• Molecular Weight :

  425.53

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  2883700-83-0