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5-LOX-IN-5

CAT: 0804-HY-149476Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-149476Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
5-LOX-IN-5 (Compound 29) is a 5-LOX inhibitor (IC50: 56 nM) . 5-LOX-IN-5 can be used for research of neurodegenerative diseases[1].
UNSPSC
12352005
Target
Lipoxygenase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/5-lox-in-5.html
Solubility
10 mM in DMSO
Smiles
OC1=CC=C(NC2=NC(C3=CC=C(N4CCOCC4)C(Br)=C3)=CS2)C=C1
Molecular Formula
C19H18BrN3O2S
Molecular Weight
432.33
References & Citations
[1]Marković A, et al. Thiazole derivatives as dual inhibitors of deoxyribonuclease I and 5-lipoxygenase: A promising scaffold for the development of neuroprotective drugs. Chem Biol Interact. 2023 Aug 25;381:110542.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported