XO/COX/LOX-IN-1

XO/COX/LOX-IN-1

• CAS Number: 2831329-35-0
• UNSPSC Description: XO/COX/LOX-IN-1 (compound 7i) is a potent xanthine oxidase/cyclooxygenases/lipoxygenases (XO/COX/LOX) inhibitor. XO/COX/LOX-IN-1 can be used in studies of inflammation, cancer and metabolic diseases[1].
• Target Antigen: COX; Lipoxygenase; Xanthine Oxidase
• Type: Reference compound
• Related Pathways: Immunology/Inflammation;Metabolic Enzyme/Protease
• Applications: Metabolism-sugar/lipid metabolism
• Field of Research: Cancer; Metabolic Disease; Inflammation/Immunology
• Assay Protocol: https://www.medchemexpress.com/xo-cox-lox-in-1.html
• Solubility: 10 mM in DMSO
• Smiles: CC1=NC2=C(C=CC=C2OCC3=NN=C(COC4=CC=CC5=C4N=C(C=C5)C)S3)C=C1
• Molecular Weight: 428.51
• References & Citations: [1]Zabiulla, et al. In-silico docking, synthesis, structure analysis, DFT calculations, energy frameworks, and pharmacological intervention of [1,3,4]-thiadiazoles analogous as XO inhibitor and on multiple molecular inflammatory targets COX and LOX. Journal of Molecular Structure. 2021 Dec;1253(1-2):132272.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported