COX-2/5-LOX-IN-3
CAT:
804-HY-147951
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
COX-2/5-LOX-IN-3
- CAS Number: 2481484-51-7
- UNSPSC Description: COX-2/5-LOX-IN-3 (compound 5b) is a potent and dual COX-2/5-LOX inhibitor with IC50 values of 45.73, 5.45 and 4.33 μM for COX-1, COX-2, and 5-LOX, respectively. COX-2/5-LOX-IN-3 has the potential for the research of inflammation diseases[1].
- Target Antigen: COX; Lipoxygenase
- Type: Reference compound
- Related Pathways: Immunology/Inflammation;Metabolic Enzyme/Protease
- Applications: COVID-19-immunoregulation
- Field of Research: Inflammation/Immunology
- Assay Protocol: https://www.medchemexpress.com/cox-2-5-lox-in-3.html
- Solubility: 10 mM in DMSO
- Smiles: O=C(NC1=C(C#N)C(C2=CC=C(Cl)C=C2)=CS1)CN3CCOCC3
- Molecular Weight: 361.85
- References & Citations: [1]Qandeel NA, et al. Synthesis, in vivo anti-inflammatory, COX-1/COX-2 and 5-LOX inhibitory activities of new 2,3,4-trisubstituted thiophene derivatives. Bioorg Chem. 2020 Sep;102:103890.
- Shipping Conditions: Room temperature
- Clinical Information: No Development Reported