COX/5-LOX-IN-1

• UNSPSC Description:

  COX/5-LOX-IN-1 (compound 6b) is a potent and dual inhibitor of COX/5-LOX with IC50s of 1.07, 0.55, and 0.28 μM for COX-1, COX-2, and 5-LOX enzyme, respectively. COX/5-LOX-IN-1 has the potential for the research of inflammation diseases[1].

• Target Antigen:

  COX

• Type:

  Reference compound

• Related Pathways:

  Immunology/Inflammation

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/cox-5-lox-in-1.html

• Solubility:

  10 mM in DMSO

• Smiles:

  CCCCCCCCCCCC1=C(C(OC)=CC(O)=C1)O

• Molecular Weight:

  294.43

• References & Citations:

  [1]Sisa M, et al. Synthesis, inhibitory activity and in silico docking of dual COX/5-LOX inhibitors with quinone and resorcinol core. Eur J Med Chem. 2020;204:112620.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  2468802-82-4