Antimalarial agent 16

CAT: 0804-HY-150066Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-150066Size:1 Each
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Description
Antimalarial agent 16 (Compound 4h) is a parasite inhibitor. Antimalarial agent 16 shows antimalarial activity, and can inhibit P. falciparum parasite growth (IC50=2.0 nM) [1].
CAS Number
[2773408-33-4]
UNSPSC
12352005
Target
Parasite
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/antimalarial-agent-16.html
Solubility
10 mM in DMSO
Smiles
CCCCC1=CC(OC2=C1C(O[C@H](C)C(N3CC4=C(C5=C(N4)C=CC=C5)C[C@H]3C(OC)=O)=O)=CC(C)=C2)=O
Molecular Formula
C30H32N2O6
Molecular Weight
516.58
References & Citations
[1]Nobuo Cho, et al. New antimalarials identified by a cell-based phenotypic approach: Structure-activity relationships of 2,3,4,9-tetrahydro-1H-β-carboline derivatives possessing a 2- ((coumarin-5-yl) oxy) alkanoyl moiety. Bioorg Med Chem. 2022 Jul 15;66:116830.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Plasmodium

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