Antimalarial agent 26

• Description :

  Antimalarial agent 26 is an orally active 1,4-naphthoquinones derivative with antimalarial activities. Antimalarial agent 26 shows cytotoxicity against P. falciparum and selectivity over mammalian cell lines. Antimalarial agent 26 inhibits P. burghei induced parasitemia in vivo[1].

• UNSPSC :

  12352005

• Target :

  Parasite

• Type :

  Reference compound

• Related Pathways :

  Anti-infection

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Infection

• Assay Protocol :

  https://www.medchemexpress.com/antimalarial-agent-26.html

• Solubility :

  10 mM in DMSO

• Smiles :

  O=C1C=C(C(C2=C1C=CC=C2)=O)NCCN3N=NC(C4(CCCCC4)O)=C3

• Molecular Formula :

  C20H22N4O3

• Molecular Weight :

  366.41

• References & Citations :

  [1]Costa Souza RM, et al. Biological activity of 1,2,3-triazole-2-amino-1,4-naphthoquinone derivatives and their evaluation as therapeutic strategy for malaria control. Eur J Med Chem. 2023 Jul 5;255:115400.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [2299199-56-5]