Antimalarial agent 24

• UNSPSC Description:

  Antimalarial agent 24 (Compound 7) is an antimalarial agent in vitro. Antimalarial agent 24 inhibits P. falciparum W2 strain with an IC50 of 0.81 μM. Antimalarial agent 24 displays a CC50 higher than 200 μM against HepG2 cells[1].

• Target Antigen:

  Parasite

• Type:

  Reference compound

• Related Pathways:

  Anti-infection

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Infection

• Assay Protocol:

  https://www.medchemexpress.com/antimalarial-agent-24.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C1C=C(C(C2=C1C=CC=C2)=O)NCCN3N=NC(C4=CC=CC=C4)=C3

• Molecular Weight:

  344.37

• References & Citations:

  [1]Costa Souza RM, et al, De Oliveira RN. Biological activity of 1,2,3-triazole-2-amino-1,4-naphthoquinone derivatives and their evaluation as therapeutic strategy for malaria control. Eur J Med Chem. 2023 Jul 5;255:115400.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  9007-83-4