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Antimalarial agent 27

CAT: 0804-HY-149882Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-149882Size:1 Each
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Description
Antimalarial agent 27 (compound 11a) is an antimalarial agent, potently targeting to P.falciparum (IC50=0.37 μM) . Antimalarial agent 27 acts function via P.falciparum DXR (1-deoxy-D-xylulose-5-phosphate reductoisomerase) inhibition (IC50=0.11 μM) [1].
CAS Number
9007-83-4
UNSPSC
12352005
Target
Parasite
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/antimalarial-agent-27.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=CC=CC=C1)N(C/C=C/P(O)(O[Na])=O)O
Molecular Formula
C10H11NNaO5P
Molecular Weight
279.16
References & Citations
[1]Wang X, et al. MEPicides: α, β-unsaturated Fosmidomycin N-Acyl Analogs as Efficient Inhibitors of Plasmodium falciparum 1-Deoxy-d-xylulose-5-phosphate reductoisomerase. ACS Infect Dis. 2023 Jul 14;9 (7) :1387-1395.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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