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HDAC-IN-58

CAT: 0804-HY-149859Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-149859Size:1 Each
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Description
HDAC-IN-58 is a HDAC inhibitor. HDAC-IN-58 has HDAC6-specific inhibition activity with an IC50 value of 2.06 nM. HDAC-IN-58 can be used for the research of chronic diseases, including neurodegenerative and psychiatric conditions[1].
CAS Number
2071224-39-8
UNSPSC
12352005
Target
HDAC
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Epigenetics
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/hdac-in-58.html
Solubility
10 mM in DMSO
Smiles
CS(=O)(N(C1=CC=CC(Cl)=C1)CC2=NC=C(C3=NN=C(C(F)F)O3)C=C2)=O
Molecular Formula
C16H13ClF2N4O3S
Molecular Weight
414.81
References & Citations
[1]Motlová L, et al. Comprehensive Mechanistic View of the Hydrolysis of Oxadiazole-Based Inhibitors by Histone Deacetylase 6 (HDAC6) . ACS Chem Biol. 2023 Jul 21;18 (7) :1594-1610.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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