HDAC-IN-85

• Target:

  DNA/RNA Synthesis|||HDAC

• Related Pathways:

  Cell Cycle/Checkpoint|||DNA Damage/DNA Repair|||Chromatin/Epigenetic

• Bioactivity:

  HDAC-IN-85 (Compound 1) is an HDAC inhibitor capable of crossing the blood-brain barrier. It exhibits inhibitory effects on brain tumor cell lines and can induce acetylation, resulting in DNA double-strand breaks and promoting RAD51 ubiquitination, which disrupts the DNA repair process. HDAC-IN-85 is applicable in studies of glioblastoma.

• Molecular Formula:

  C24H27FN4O5

• Molecular Weight:

  470.49

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C