HDAC-IN-47

CAT: 0931-T62072-01Size: 25 mgDry Ice: NoHazardous: No
CAT#:0931-T62072-01Size:25 mg
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PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
Others|||HDAC
Related Pathways
Others|||DNA Damage/DNA Repair|||Chromatin/Epigenetic
Bioactivity
HDAC-IN-47 is an orally active histone deacetylase (HDAC) inhibitor, with IC50 values of 19.75 nM, 57.8 nM, 40.27 nM, 5.63 nM, and 302.73 nM for HDAC1, HDAC2, HDAC3, HDAC6, and HDAC8, respectively. HDAC-IN-47 can block the cell cycle in the G2/M phase, inhibit autophagy, induce apoptosis via the Bax/Bcl-2 and caspase-3 pathways, and exhibits anti-cancer activity in vivo.
Molecular Formula
C17H20BrN3O4
Molecular Weight
410.26
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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