HDAC-IN-47
- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
HDAC-IN-47
Target :
Others|||HDACRelated Pathways :
Others|||DNA Damage/DNA Repair|||Chromatin/EpigeneticBioactivity :
HDAC-IN-47 is an orally active histone deacetylase (HDAC) inhibitor, with IC50 values of 19.75 nM, 57.8 nM, 40.27 nM, 5.63 nM, and 302.73 nM for HDAC1, HDAC2, HDAC3, HDAC6, and HDAC8, respectively. HDAC-IN-47 can block the cell cycle in the G2/M phase, inhibit autophagy, induce apoptosis via the Bax/Bcl-2 and caspase-3 pathways, and exhibits anti-cancer activity in vivo.Molecular Formula :
C17H20BrN3O4Molecular Weight :
410.26Shipping Conditions :
Cool packStorage Temperature :
-20°C
