STING agonist-34

CAT: 0804-HY-149781-01Size: 1 mgDry Ice: NoHazardous: No
CAT#: HY-149781-01Size: 1 mg
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AVAILABILITY
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
STING agonist-34 (Compound 12L) is a potent STING agonist with an IC50 value of 1.15 μM and an EC50 of 0.38 μM in THP1 cells. STING agonist-34 could be used in cancer research[1].
CAS Number
[2913152-30-2]
UNSPSC
12352005
Target
STING
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/sting-agonist-34.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=CC(F)=C(C=C1NC(C2=CC=C(C3=CC=NN=C3)N=N2)=O)C#C)O
Molecular Formula
C18H10FN5O3
Molecular Weight
363.30
References & Citations
[1]Li R, et al. Loops Mediate Agonist-Induced Activation of the Stimulator of Interferon Genes Protein. J Chem Inf Model. 2023 Oct 13.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported