Bcl-2-IN-15

• UNSPSC Description:

  Bcl-2-IN-15 (Compound 13d)) is a Bcl-2 inhibitor (IC50: 363 nM). Bcl-2-IN-15 inhibits the proliferation ofNCI leukemia cancer cell line[1].

• Target Antigen:

  Bcl-2 Family

• Type:

  Reference compound

• Related Pathways:

  Apoptosis

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/bcl-2-in-15.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(C1=CC(SC(NC(C2=CC=C(NCCC3=CC=CC=C3)C([N+]([O-])=O)=C2)=O)=N4)=C4C=C1)NC5=CC=C(C=C5)OCC6=CC=C(C(F)(F)F)C=C6

• Molecular Weight:

  711.71

• References & Citations:

  [1]Ismail HS, et al. Design, molecular modelling and synthesis of novel benzothiazole derivatives as BCL-2 inhibitors. Sci Rep. 2023 Sep 20;13(1):15554.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported