Bcl-2-IN-21

• UNSPSC Description:

  Bcl-2-IN-21 (compound C1) is an iridium compound with anticancer activity that targets and inhibits Bcl-2. Bcl-2-IN-21 inhibits colony formation of cancer cells and induces elevated levels of Bax and caspase 3[1].

• Target Antigen:

  Bcl-2 Family

• Type:

  Reference compound

• Related Pathways:

  Apoptosis

• Field of Research:

  cancer

• Assay Protocol:

  https://www.medchemexpress.com/bcl-2-in-21.html

• Smiles:

  FP(F)(F)(F)(F)F.C1(C=CC=C2)=[N]2[Ir]34([N]5=C(C6=[N]4C(C=CC=C7)=C7N6CC8=CC=CC=C8)C=CC9=CC=CC=C59)([N]%10=C(C=CC=C%10)C%11=CC=CC=C%113)C%12=CC=CC=C1%12

• Molecular Weight:

  980.96

• References & Citations:

  [1]New cyclometalated iridium(III) complexes bearing substituted 2-(1H-benzimidazol-2-yl)quinoline: Synthesis, characterization, electrochemical and anticancer studies

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported