Bcl-2-IN-9
CAT:
804-HY-149009
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Bcl-2-IN-9
- CAS Number: 2490542-33-9
- UNSPSC Description: Bcl-2-IN-9 is a novel proapoptotic Bcl-2 inhibitor with IC50 value of 2.9 μM and low cytotoxic. Bcl-2-IN-9 mediates apoptosis by down-regulating expression of Bcl-2 in cancer cells and has a high selectivity against leukemia cells[1].
- Target Antigen: Apoptosis; Bcl-2 Family
- Type: Reference compound
- Related Pathways: Apoptosis
- Applications: Cancer-programmed cell death
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/bcl-2-in-9.html
- Solubility: 10 mM in DMSO
- Smiles: CN1CCN(C2=NC3=CC=CC=C3N=C2SC4=NN=C(C5=CC=C(OCCN6CCOCC6)C=C5)O4)CC1
- Molecular Weight: 533.65
- References & Citations: [1]Yukari Ono, et al. Design and synthesis of quinoxaline-1,3,4-oxadiazole hybrid derivatives as potent inhibitors of the anti-apoptotic Bcl-2 protein. Bioorg Chem. 2020 Aug; 104: 104245.
- Shipping Conditions: Room temperature
- Clinical Information: No Development Reported