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Bcl-2-IN-18

CAT: 0804-HY-163308Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-163308Size:1 Each
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Description
Bcl-2-IN-18 (Compound 23) is a breast cancer Bcl-2 inhibitor with a IC50 value of 4.7 μM for MCF-7. Bcl-2-IN-18 has antitumor activity[1].
UNSPSC
12352005
Target
Bcl-2 Family
Type
Reference compound
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/bcl-2-in-18.html
Solubility
10 mM in DMSO
Smiles
O=S(C1=CC=C2N(C3CCCCC3)C(C4=CC=C(Cl)C=C4)=NC2=C1)(C)=O
Molecular Formula
C20H21ClN2O2S
Molecular Weight
388.91
References & Citations
[1]Abbade Y, et al. Synthesis, Anticancer Activity, and In Silico Modeling of Alkylsulfonyl Benzimidazole Derivatives: Unveiling Potent Bcl-2 Inhibitors for Breast Cancer. ACS Omega, 2024.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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