Bcl-2-IN-18

Bcl-2-IN-18

• UNSPSC Description: Bcl-2-IN-18 (Compound 23) is a breast cancer Bcl-2 inhibitor with a IC50 value of 4.7 μM for MCF-7. Bcl-2-IN-18 has antitumor activity[1].
• Target Antigen: Bcl-2 Family
• Type: Reference compound
• Related Pathways: Apoptosis
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/bcl-2-in-18.html
• Solubility: 10 mM in DMSO
• Smiles: O=S(C1=CC=C2N(C3CCCCC3)C(C4=CC=C(Cl)C=C4)=NC2=C1)(C)=O
• Molecular Weight: 388.91
• References & Citations: [1]Abbade Y, et al. Synthesis, Anticancer Activity, and In Silico Modeling of Alkylsulfonyl Benzimidazole Derivatives: Unveiling Potent Bcl-2 Inhibitors for Breast Cancer. ACS Omega, 2024.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported