NF-κB-IN-10

CAT: 0804-HY-149351Size: 1 EachDry Ice: NoHazardous: No

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CAT#:0804-HY-149351Size:1 Each

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Description

NF-κB-IN-10 (compound E1) is an NF-κB inhibitor that can improve heart failure by reducing oxidative stress and inflammation by regulating Nrf2/NF-κB signaling pathway. NF-κB-IN-10 inhibits LPS-induced NO production and expression of iNOS and COX-2 in RAW264.7 cells. NF-κB-IN-10 can be used in the research of cardiovascular diseases[1].

CAS Number

3052257-09-4

UNSPSC

12352005

Target

NF-κB

Type

Reference compound

Related Pathways

NF-κB

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/nf-κb-in-10.html

Solubility

10 mM in DMSO

Smiles

CC(N1N=C(C)CC1C2=C(OC)C=C(OC)C=C2/C=C/C3=CC=C(OCCCC)C=C3)=O

Molecular Formula

C26H32N2O4

Molecular Weight

436.54

References & Citations

[1]Yang X, et al. Novel pterostilbene derivatives ameliorate heart failure by reducing oxidative stress and inflammation through regulating Nrf2/NF-κB signaling pathway. Eur J Med Chem. 2023 Oct 5;258:115602.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

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Alternative Products

Catalog	Name
T78750-01	NF-κB-IN-10
sc-8414	NFκB p50 (E-10)
sc-8414 HRP	NFκB p50 (E-10) HRP
sc-8414 FITC	NFκB p50 (E-10) FITC
GS056A	EMSA Probe NF-κB (10μM)
sc-8414 PE	NFκB p50 (E-10) PE
sc-8414 AC	NFκB p50 (E-10) AC
sc-8414 X	NFκB p50 (E-10) X
GS056T	Mutant EMSA Probe NF-κB (10μM)
MBS5820412	NF-kappaB-IN-10

NF-κB-IN-10

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