PD-1/PD-L1-IN-28

PD-1/PD-L1-IN-28

• CAS Number: 2499965-07-8
• UNSPSC Description: PD-1/PD-L1-IN-28 (compound 3) is an immune checkpoint inhibitor of PD-1/PD-L1 signaling pathway (IC50=0.744 µM). PD-1/PD-L1-IN-28 shows good research potential in tumor immunity[1].
• Target Antigen: PD-1/PD-L1
• Type: Reference compound
• Related Pathways: Immunology/Inflammation
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/pd-1-pd-l1-in-28.html
• Solubility: 10 mM in DMSO
• Smiles: OCCNCC1=CC=C(NC2=NN=C(C3=C(C)C(C4=CC=CC=C4)=CC=C3)O2)C=C1
• Molecular Weight: 400.47
• References & Citations: [1]Jiang Sheng, et al. Preparation of phenyl substituted five membered heterocyclic compounds as immunocheckpoint inhibitors of PD-1 / PD-L1 signaling pathway. Patent WO2021031788A1.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported